Diversity in primary structure and function of neuronal nicotinic acetylcholine receptor channels
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Cited by (186)
Nicotinic modulation of intrinsic brain networks in schizophrenia
2013, Biochemical PharmacologyCitation Excerpt :Upon activation, the primary function of nicotinic receptors is to depolarize the cell. This depolarizing current is carried by an influx of sodium through α4β2 receptors, and an influx of calcium through α7 receptors [4]. The influx of calcium through presynaptic α7 receptors also activates second-messenger systems that can induce the release of neurotransmitters into the synaptic cleft [5].
Ligand-gated ion channels
2012, Cell Physiology Source BookLigand-Gated Ion Channels
2011, Cell Physiology Source Book: Essentials of Membrane BiophysicsCellular events in nicotine addiction
2009, Seminars in Cell and Developmental BiologyDemonstration of functional α4-containing nicotinic receptors in the medial habenula
2009, NeuropharmacologyThe Drosophila acetylcholine receptor subunit Dα5 is part of an α-bungarotoxin binding acetylcholine receptor
2005, Journal of Biological ChemistryCitation Excerpt :The observed sedimentation coefficient of 9.2 S is close to the sedimentation coefficient for the receptor from T. californica (9 S). The calculated mass of 270 kDa is also similar to other nAChRs (for reviews, see Refs. 5, 6, 43, and 44). The pharmacological profile of the receptor resembles the pharmacology of AchR of the cockroach (Planetaria americana) (45).