Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics
Section snippets
Acknowledgements
The author would like to acknowledge the contributions of Jennifer Shenk, Linda Moore, Stacey Jones, and Steven Kliewer from the Department of Molecular Endocrinology, GlaxoWellcome, Inc.; Geraldine Hamilton, Summer Jolley, James Coon, and Darryl Gilbert from the Division of Drug Delivery and Disposition, School of Pharmacy, University of North Carolina at Chapel Hill; and Bingfang Yan from the Department of Biomedical Sciences, University of Rhode Island.
References (14)
- et al.
Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes
Toxicol. Appl. Pharmacol.
(1993) - et al.
An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway
Cell
(1998) - et al.
Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation
Arch. Biochem. Biophys.
(1999) The CYP3A family
Regulation of the glucocorticoid-inducible cytochromes P450
- et al.
Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocyes
Drug Met. Dispos.
(1995) - et al.
Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes
Mol. Pharmacol.
(1996)
There are more references available in the full text version of this article.
Cited by (0)
Copyright © 2001 Elsevier Science Ireland Ltd. All rights reserved.