mRNA polyadenylation and its coupling to other RNA processing reactions and to transcription

https://doi.org/10.1016/S0955-0674(99)80049-0Get rights and content

Eukaryotic mRNA precursors are processed at their 3′ ends by a coupled cleavage/polyadenylation reaction. In recent years, most of the factors involved in 3′-end processing have been identified and evidence has been presented for the coupling of mRNA 3′-end formation to capping, splicing and transcription. These links are important for the quality control of the mRNA during synthesis.

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