Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Volume 1843, Issue 11, November 2014, Pages 2543-2555
ReviewNR4A nuclear receptors are orphans but not lonesome
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Graphical abstract
Abbreviations
6-MP
6-mercaptopurine
9-cis-RA
9-cis-retinoic acid
AMP
adenosine monophosphate
AMPK
AMP-activated protein kinase
Cam-kinase
calcium/calmodulin-dependent protein kinase
CREB
cAMP response element binding protein
DBD
DNA-binding domain
DSB
DNA double-strand break
E2
17-β-estradiol
HAT
histone acetyltransferase
HDAC
histone deacetylase
HIF-1α
hypoxia inducible factor-1α
HPA
hypothalamo-pituitary-adrenal
LBD
ligand-binding domain
LXRs
liver X receptors
MDM2
mouse double minute 2
NBRE
NGFI-B response element
NES
nuclear export sequence
N-term
amino-terminal domain
NurRE
Nur-response elements
PI3K
phosphatidylinositol 3-kinase
PIP3
phosphatidylinositol(3,4,5)phosphate
PKC
protein kinase C
POMC
pro-opiomelanocortin
PPARs
peroxisome proliferator-activated receptors
βRARE
RA-response element of the RARβ promoter
RXRs
retinoid X receptors
StAR
steroidogenic acute regulatory protein
Treg
regulatory T cells
Keywords
Nuclear receptor
Protein–protein interaction
Nur77
Nurr1
NOR-1
NR4A
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These authors contributed equally.
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