Journal of Molecular Biology
CommunicationCarbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions
Section snippets
Protein Data Bank accession number
Coordinates and structure factors of the Man9GlcNAc2 glycoform of human IgG1-Fc have been deposited in the Protein Data Bank with accession number 2WAH.
Acknowledgements
We thank W. Lu for technical assistance with tissue culture and the staff of BM-14 at the European Radiation Synchrotron Facility. This work was funded by Cancer Research UK, the UK Medical Research Council, the European Commission as SPINE2 Complexes (FP6-RTD-031220), and the Wellcome Trust. We also thank the Wellcome Trust and the Biotechnology and Biological Sciences Research Council for equipment grants to the Glycobiology Institute to purchase the Q-Tof and TofSpec mass spectrometers,
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M.C. and T.A.B. contributed equally to this work.