cAMP and protein kinase A contribute to the downregulation of spinal glutamate transporters after chronic morphine
Section snippets
Acknowledgements
This work was supported by PHS Grants RO1 DA08835, NS42661, and NS45681 to J.M.
References (35)
Glutamate uptake
Prog. Neurol.
(2001)- et al.
The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-l-arginine, attenuate analgesic tolerance to the mu?opioid morphine but not to kappa opioids
Pain
(1994) - et al.
Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal
Neuron
(2001) - et al.
Regulation of opioid receptor traffickking and morphine tolerance by receptor oligomerization
Cell
(2002) - et al.
Continuous co-administration of dextromethorphan or MK-801 with morphine: attenuation of morphine dependence and naloxone-reversible attenuation of morphine tolerance
Pain
(1996) - et al.
Experimental mononeuropathy reduces the antinociceptive effects of morphine: implications for common intracellular mechanisms involved in morphine tolerance and neuropathic pain
Pain
(1995) - et al.
Inhibition of morphine tolerance and dependence by MS-153, a glutamate transporter activator
Eur. J. Pharmacol.
(2001) - et al.
Amyotrophic lateral sclerosis-linked glutamate transporter mutation has impaired glutamate clearance capacity
J. Biol. Chem.
(2001) - et al.
Chronic catheterization of the spinal subarachnoid space
Physiol. Behav.
(1976) - et al.
Different mechanisms mediate development and expression of tolerance and dependence for peripheral-opioid antinociception in rat
J. Neurosci.
(1997)
Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence
Nature
(2000)
Enhanced morphine analgesia in mice lacking beta-arrestin-2
Science
(1999)
A method for determining loss of pain sensation
J. Pharmacol. Exp. Ther.
(1941)
Regional deafferentation downregulates subtypes of glutamate transporter protein
J. Neurochem.
(1995)
Opioid tolerance and the emergence of new opioid receptro-coupled signaling
Mol. Neurobiol.
(2001)
Chronic morphine increases GABA tone on serotonergic neurons of the dorsal raphe nucleus: association with an up-regulation of the cyclic AMP pathway
Neuroscience
(2000)
Characterization of striatal lesions produced by glutamate uptake alteration: cell death, reactive gliosis, and changes in GLT?1 and GADD45 mRNA expression
Glia
(2000)
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