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Enzymatic synthesis of nucleotide sugars

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Abstract

The present review gives a survey on the biosynthetic pathways of nucleotide sugars which are important for the in vitro synthesis of mammalian glycoconjugates. With respect to the use of these enzymes in glycotechnology the availability as recombinant enzymes from different sources, the large-scale synthesis of nucleotide sugars and their in situ regeneration in combination with glycosyltransferases are summarized and evaluated.

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  1. Institute of Enzyme Technology, University of Düsseldorf, Research Center Jülich, 52426, Jülich, Germany

    Thomas Bülter & Lothar Elling

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  1. Thomas Bülter
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Bülter, T., Elling, L. Enzymatic synthesis of nucleotide sugars. Glycoconj J 16, 147–159 (1999). https://doi.org/10.1023/A:1026444726698

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