Fast transmission between nerve cells relies on specialized ion channels. Probing the structure of these proteins reveals how the binding of a neurotransmitter causes the communication channels to open.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Chakrapani, S. & Auerbach, A. Proc. Natl Acad. Sci. USA 102, 87–92 (2004).
Lee, W. Y. & Sine, S. M. Nature 438, 243–247 (2005).
Lummis, S. C. R. et al. Nature 438, 248–252 (2005).
Unwin, N. J. Mol. Biol. 346, 967–989 (2005).
Hu, X. Q., Zhang, L., Stewart, R. R. & Weight, R. R. Nature 421, 272–275 (2003).
Kash, T. L. et al. Nature 421, 272–275 (2004).
Kash, T. L., Dizon, M. J., Trudell, J. R. & Harrison, N. L. J. Biol. Chem. 279, 4887–4893 (2004).
Chakrapani, S., Bailey, T. D. & Auerbach, A. J. Gen. Physiol. 123, 341–356 (2004).
Miyazawa, A., Fujiyoshi, Y. & Unwin, N. Nature 423, 949–955 (2003).
Lester, H. A., Dibas, M. I., Dahan, D. S., Leite, J. F. & Doughtery, D. A. Trends Neurosci. 27, 329–336 (2004).
Reeves, D. C., Jansen, M., Bali, M., Lemster, T. & Akabas, M. J. Neurosci. 25, 9358–9366 (2005).
Samson, M. S. P. & Weinstein, H. Trends Pharmacol. Sci. 21, 445–451 (2000).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Czajkowski, C. Triggers for channel opening. Nature 438, 167–168 (2005). https://doi.org/10.1038/438167a
Published:
Issue Date:
DOI: https://doi.org/10.1038/438167a
