Abstract
We investigated the gene expression of three monoamine transporters (norepinephrine transporter, NET; serotonin transporter, SERT; and dopamine transporter, DAT) in the rat superior cervical ganglion (SCG). Most of principal ganglion neurons abundantly expressed NET mRNA. In addition, about 30% of principal ganglion neurons also expressed SERT mRNA. However, DAT mRNA expression was not observed there. These results suggest that serotonin as well as norepinephrine works as a neurotransmitter in a subset of principal ganglion neurons.
Copyright 1999 Elsevier Science B.V.
MeSH terms
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Animals
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Carrier Proteins / genetics*
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Dopamine Plasma Membrane Transport Proteins
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Gene Expression / physiology
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In Situ Hybridization
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Locus Coeruleus / chemistry
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Locus Coeruleus / physiology
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Male
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Membrane Glycoproteins / genetics*
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Membrane Transport Proteins*
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Nerve Tissue Proteins / genetics
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Norepinephrine Plasma Membrane Transport Proteins
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Oligonucleotide Probes
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RNA, Messenger / analysis
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Rats
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Rats, Wistar
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Serotonin Plasma Membrane Transport Proteins
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Superior Cervical Ganglion / chemistry*
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Superior Cervical Ganglion / physiology
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Symporters*
Substances
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Carrier Proteins
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Dopamine Plasma Membrane Transport Proteins
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Membrane Glycoproteins
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Membrane Transport Proteins
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Nerve Tissue Proteins
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Norepinephrine Plasma Membrane Transport Proteins
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Oligonucleotide Probes
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RNA, Messenger
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Serotonin Plasma Membrane Transport Proteins
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Slc6a2 protein, rat
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Slc6a3 protein, rat
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Slc6a4 protein, rat
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Symporters