Polymorphism of the cytochrome P450 (CYP) 2C9 gene in Japanese epileptic patients: genetic analysis of the CYP2C9 locus

Pharmacogenetics. 2000 Feb;10(1):85-9. doi: 10.1097/00008571-200002000-00011.
No abstract available

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Amino Acid Substitution
  • Aryl Hydrocarbon Hydroxylases*
  • Cytochrome P-450 CYP2C9
  • Cytochrome P-450 Enzyme System / genetics*
  • Epilepsy / blood
  • Epilepsy / drug therapy
  • Epilepsy / genetics*
  • Exons / genetics
  • Humans
  • Japan
  • Mutation*
  • Phenytoin / analogs & derivatives
  • Phenytoin / blood
  • Phenytoin / therapeutic use
  • Polymerase Chain Reaction
  • Polymorphism, Genetic / genetics*
  • Polymorphism, Restriction Fragment Length
  • Steroid 16-alpha-Hydroxylase*
  • Steroid Hydroxylases / genetics*

Substances

  • hydroxyphenytoin
  • Phenytoin
  • Cytochrome P-450 Enzyme System
  • Steroid Hydroxylases
  • CYP2C9 protein, human
  • Cytochrome P-450 CYP2C9
  • Aryl Hydrocarbon Hydroxylases
  • Steroid 16-alpha-Hydroxylase