Abstract
Preliminary SAR studies on the side chain of a new class of antiviral nucleosides have shown that terminal substitution in the side-chain, with a halogen atom, lead to potent and highly specific anti-VZV agents.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antiviral Agents / chemistry
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Antiviral Agents / pharmacology*
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Halogens / chemistry*
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Herpesvirus 3, Human / drug effects*
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Nucleosides / chemistry
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Nucleosides / pharmacology*
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Structure-Activity Relationship
Substances
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Antiviral Agents
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Halogens
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Nucleosides