Abstract
Recent analyses of the genes required for autophagy--intracellular bulk protein degradation--in yeast have revealed two ubiquitin-like systems, both of which are involved in the membrane dynamics of the process. Molecular dissection of these systems is now revealing some surprises.
MeSH terms
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Autophagy / physiology*
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Autophagy-Related Protein 7
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Autophagy-Related Protein 8 Family
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Lysosomes / metabolism
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Microscopy, Electron
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Microtubule-Associated Proteins / metabolism
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Models, Biological
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Proteins / metabolism
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Saccharomyces cerevisiae / physiology*
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Saccharomyces cerevisiae / ultrastructure
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Saccharomyces cerevisiae Proteins*
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Ubiquitins / metabolism*
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Vacuoles / metabolism
Substances
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ATG7 protein, S cerevisiae
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ATG8 protein, S cerevisiae
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Autophagy-Related Protein 8 Family
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Microtubule-Associated Proteins
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Proteins
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Saccharomyces cerevisiae Proteins
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Ubiquitins
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Autophagy-Related Protein 7