Abstract
Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Calcium-Calmodulin-Dependent Protein Kinases / antagonists & inhibitors
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Calcium-Calmodulin-Dependent Protein Kinases / metabolism*
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Diabetes Mellitus, Type 2 / physiopathology
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Drosophila melanogaster / embryology
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Embryo, Nonmammalian / physiology
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Enzyme Inhibitors / pharmacology
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Glycogen / biosynthesis
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Glycogen Synthase Kinases
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Humans
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Insulin / physiology
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Phosphorylation
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Protein Biosynthesis
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Signal Transduction
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Substrate Specificity
Substances
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Enzyme Inhibitors
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Insulin
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Glycogen
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Glycogen Synthase Kinases
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Calcium-Calmodulin-Dependent Protein Kinases