Enzymatic thiolysis of azathioprine in vitro

Biochem Pharmacol. 1976 Nov 1;25(21):2421-6. doi: 10.1016/0006-2952(76)90044-7.
No abstract available

MeSH terms

  • Animals
  • Azathioprine / metabolism*
  • Enzyme Induction / drug effects
  • Glutathione / metabolism
  • Hydrogen-Ion Concentration
  • In Vitro Techniques
  • Kinetics
  • Liver / enzymology*
  • Male
  • Mercaptopurine / metabolism
  • Phenobarbital / pharmacology
  • Rats

Substances

  • Mercaptopurine
  • Glutathione
  • Azathioprine
  • Phenobarbital