Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases

Chem Rev. 2003 Jun;103(6):2239-304. doi: 10.1021/cr000068x.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Binding Sites
  • Catalysis
  • Fatty Acids, Unsaturated / chemistry*
  • Fatty Acids, Unsaturated / metabolism
  • Free Radicals / chemistry
  • Free Radicals / metabolism
  • Humans
  • Models, Molecular
  • Oxidation-Reduction
  • Prostaglandin-Endoperoxide Synthases / chemistry*
  • Prostaglandin-Endoperoxide Synthases / metabolism
  • Protein Conformation
  • Substrate Specificity

Substances

  • Fatty Acids, Unsaturated
  • Free Radicals
  • Prostaglandin-Endoperoxide Synthases