Function of caveolae in Ca2+ entry and Ca2+-dependent signal transduction

Masashi Isshiki; Richard G W Anderson

doi:10.1034/j.1600-0854.2003.00130.x

Function of caveolae in Ca2+ entry and Ca2+-dependent signal transduction

Traffic. 2003 Nov;4(11):717-23. doi: 10.1034/j.1600-0854.2003.00130.x.

Authors

Masashi Isshiki¹, Richard G W Anderson

Affiliation

¹ Department of Nephrology and Endocrinology, University of Tokyo, Tokyo 113-8655, Japan.

PMID: 14617355
DOI: 10.1034/j.1600-0854.2003.00130.x

Abstract

The correct spatial and temporal control of Ca2+ signaling is essential for such cellular activities as fertilization, secretion, motility, and cell division. There has been a long-standing interest in the role of caveolae in regulating intracellular Ca2+ concentration. In this review we provide an updated view of how caveolae may regulate both Ca2+ entry into cells and Ca2+-dependent signal transduction

Publication types

Review

MeSH terms

Animals
Calcium / metabolism*
Calcium Channels / metabolism
Calcium Signaling / physiology*
Caveolae / metabolism*
Cell Membrane / metabolism
Inositol 1,4,5-Trisphosphate / metabolism
Inositol 1,4,5-Trisphosphate Receptors
Muscle, Skeletal / metabolism
Receptors, Cytoplasmic and Nuclear / metabolism
Time Factors

Substances

Calcium Channels
Inositol 1,4,5-Trisphosphate Receptors
Receptors, Cytoplasmic and Nuclear
Inositol 1,4,5-Trisphosphate
Calcium