Furosemide analogues as potent inhibitors of the new permeability pathways of Plasmodium falciparum-infected human erythrocytes

Mol Biochem Parasitol. 2004 Feb;133(2):315-8. doi: 10.1016/j.molbiopara.2003.10.009.

Authors

Henry M Staines¹, Belinda C Dee, Martin O'Brien, Hans-Jochen Lang, Heinrich Englert, Heather A Horner, J Clive Ellory, Kiaran Kirk

Affiliation

¹ University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK. henry.staines@physiol.ox.ac.uk

PMID: 14698443
DOI: 10.1016/j.molbiopara.2003.10.009

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biological Transport / drug effects
Cell Membrane Permeability / drug effects*
Choline / metabolism*
Dose-Response Relationship, Drug
Erythrocytes / metabolism
Erythrocytes / parasitology*
Furosemide / analogs & derivatives*
Furosemide / pharmacology*
Humans
Plasmodium falciparum / growth & development
Plasmodium falciparum / pathogenicity*

Substances

Furosemide
Choline