Small RNAs shed some light

Cell. 2004 Jul 9;118(1):1-2. doi: 10.1016/j.cell.2004.06.024.

Abstract

Small regulatory RNAs can act by pairing with their target messages, targeting themselves and the mRNA for degradation; Lenz et al. (this issue of Cell) now report that multiple small RNAs are essential regulators of the quorum-sensing systems of Vibrio species, including the regulation of virulence in V. cholerae.

Publication types

  • Comment

MeSH terms

  • Gene Expression Regulation, Bacterial*
  • Genes, Bacterial
  • Genes, Reporter
  • Luminescent Measurements
  • MicroRNAs / genetics
  • MicroRNAs / metabolism*
  • Mutation
  • Phosphorylation
  • Promoter Regions, Genetic
  • Signal Transduction
  • Trans-Activators / metabolism
  • Vibrio / genetics
  • Vibrio / physiology*
  • Vibrio cholerae / genetics
  • Vibrio cholerae / pathogenicity
  • Vibrio cholerae / physiology*
  • Virulence

Substances

  • MicroRNAs
  • Trans-Activators