Marine actinomycetes as a source of novel secondary metabolites

Hans-Peter Fiedler; Christina Bruntner; Alan T Bull; Alan C Ward; Michael Goodfellow; Olivier Potterat; Carsten Puder; Gerhard Mihm

doi:10.1007/s10482-004-6538-8

Marine actinomycetes as a source of novel secondary metabolites

Antonie Van Leeuwenhoek. 2005 Jan;87(1):37-42. doi: 10.1007/s10482-004-6538-8.

Authors

Hans-Peter Fiedler¹, Christina Bruntner, Alan T Bull, Alan C Ward, Michael Goodfellow, Olivier Potterat, Carsten Puder, Gerhard Mihm

Affiliation

¹ Mikrobiologisches Institut, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany. hans-peter.fiedler@uni-tuebingen.de

PMID: 15726289
DOI: 10.1007/s10482-004-6538-8

Abstract

A set of 600 actinomycetes strains which were isolated from marine sediments from various sites in the Pacific and Atlantic Oceans were screened for the production of bioactive secondary metabolites. Marine streptomycete strains were found to be producers of well known chemically diverse antibiotics isolated from terrestrial streptomycetes, as in the case of marine Micromonospora strains. New marine members of the rare genus Verrucosispora seem to be a promising source for novel bioactive secondary metabolites as shown in the case of the abyssomicin producing strain AB-18-032.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Actinomycetales / classification
Actinomycetales / growth & development
Actinomycetales / isolation & purification*
Actinomycetales / metabolism*
Anti-Bacterial Agents / chemistry*
Anti-Bacterial Agents / isolation & purification*
Atlantic Ocean
Culture Media / chemistry
Geologic Sediments / microbiology*
Micromonosporaceae / classification
Micromonosporaceae / growth & development
Micromonosporaceae / isolation & purification
Micromonosporaceae / metabolism
Molecular Structure
Pacific Ocean
Seawater

Substances

Anti-Bacterial Agents
Culture Media