Abstract
Thermophilic cytochrome P450 enzymes are of potential interest from structural, mechanistic, and biotechnological points of view. The structures and properties of two such enzymes, CYP119 and CYP175A1, have been investigated and provide the foundation for future work on thermophilic P450 enzymes.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Archaeal Proteins
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Cytochrome P-450 Enzyme System / chemistry*
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Cytochrome P-450 Enzyme System / genetics
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Cytochrome P-450 Enzyme System / metabolism
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Cytochrome P-450 Enzyme System / physiology
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Hot Temperature*
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Mixed Function Oxygenases / chemistry*
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Mixed Function Oxygenases / genetics
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Mixed Function Oxygenases / metabolism
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Mixed Function Oxygenases / physiology
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Oxygenases / chemistry*
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Oxygenases / genetics
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Oxygenases / metabolism
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Oxygenases / physiology
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Sulfolobus solfataricus / enzymology
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Thermus thermophilus / enzymology
Substances
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Archaeal Proteins
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Cytochrome P-450 Enzyme System
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Mixed Function Oxygenases
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Oxygenases
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beta-carotene hydroxylase
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CYP119 protein, Sulfolobus solfataricus