From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates

Invest New Drugs. 2006 Jan;24(1):37-77. doi: 10.1007/s10637-005-4541-1.
No abstract available

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biological Transport
  • Clinical Trials, Phase II as Topic
  • Clinical Trials, Phase III as Topic
  • Drug Resistance, Neoplasm
  • Folic Acid Antagonists / pharmacology
  • Folic Acid Antagonists / therapeutic use*
  • Glutamates / pharmacology
  • Glutamates / therapeutic use*
  • Guanine / analogs & derivatives*
  • Guanine / pharmacology
  • Guanine / therapeutic use
  • Humans
  • Methotrexate / pharmacology
  • Methotrexate / therapeutic use*
  • Neoplasms / drug therapy*
  • Pemetrexed
  • Randomized Controlled Trials as Topic

Substances

  • Antineoplastic Agents
  • Folic Acid Antagonists
  • Glutamates
  • Pemetrexed
  • Guanine
  • Methotrexate