Insights into the physiology of childbirth using transcriptomics

PLoS Med. 2006 Jun;3(6):e276. doi: 10.1371/journal.pmed.0030276.

Abstract

Romero and colleagues discuss a study in PLoS Medicine that used microarrays to determine labor-associated gene expression profiles in the human uterus.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Cesarean Section
  • Female
  • Gene Expression Profiling
  • Gene Expression Regulation
  • Genomics*
  • Humans
  • Oligonucleotide Array Sequence Analysis
  • Parturition / physiology*
  • Pregnancy
  • Prohibitins
  • Repressor Proteins / genetics
  • Repressor Proteins / metabolism
  • Research Design
  • Retinoid X Receptor alpha / genetics
  • Retinoid X Receptor alpha / metabolism
  • Transcription, Genetic*
  • Uterine Contraction / genetics*
  • Uterine Contraction / metabolism
  • Uterus / metabolism*

Substances

  • Prohibitins
  • Repressor Proteins
  • Retinoid X Receptor alpha