Hyperbilirubinemia and kernicterus

Steven M Shapiro; Vinod K Bhutani; Lois Johnson

doi:10.1016/j.clp.2006.03.010

Hyperbilirubinemia and kernicterus

Clin Perinatol. 2006 Jun;33(2):387-410. doi: 10.1016/j.clp.2006.03.010.

Authors

Steven M Shapiro¹, Vinod K Bhutani, Lois Johnson

Affiliation

¹ Division of Child Neurology, Department of Neurology, Virginia Commonwealth University Medical Center, Virginia Commonwealth University, Richmond, 23298-0211, USA. sshapiro@vcu.edu

PMID: 16765731
DOI: 10.1016/j.clp.2006.03.010

Abstract

This article describes new findings concerning the basic science of bilirubin neurotoxicity, new considerations of the definition of clinical kernicterus, and new and useful tools to diagnose kernicterus in older children, and discusses treatments for kernicterus beyond the newborn period and why proper diagnosis is important.

Publication types

Review

MeSH terms

Bilirubin / blood
Child Development
Humans
Hyperbilirubinemia, Neonatal / complications*
Hyperbilirubinemia, Neonatal / diagnosis
Hyperbilirubinemia, Neonatal / physiopathology
Hyperbilirubinemia, Neonatal / therapy
Infant, Newborn
Kernicterus / diagnosis
Kernicterus / etiology*
Kernicterus / physiopathology
Kernicterus / therapy
Neonatal Screening

Substances

Bilirubin