Transnitrosation of thiols from aliphatic N-nitrosamines: S-nitrosation and indirect generation of nitric oxide

J Am Chem Soc. 2007 Jan 31;129(4):736-7. doi: 10.1021/ja0658259.

Authors

Takahiro Yanagimoto¹, Takeshi Toyota, Norio Matsuki, Yumi Makino, Seiichi Uchiyama, Tomohiko Ohwada

Affiliation

¹ Laboratory of Organic and Medicinal Chemistry and Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

PMID: 17243790
DOI: 10.1021/ja0658259

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bridged Bicyclo Compounds, Heterocyclic / chemical synthesis
Bridged Bicyclo Compounds, Heterocyclic / chemistry*
Bridged Bicyclo Compounds, Heterocyclic / pharmacology*
Drug Design
Muscle, Smooth / drug effects
Nitric Oxide / biosynthesis
Nitric Oxide Donors / chemical synthesis
Nitric Oxide Donors / chemistry*
Nitric Oxide Donors / pharmacology*
Nitrosamines / chemical synthesis
Nitrosamines / chemistry*
Nitrosamines / pharmacology*
Nitrosation
Rats
Sulfhydryl Compounds / chemistry
Sulfhydryl Compounds / metabolism

Substances

Bridged Bicyclo Compounds, Heterocyclic
Nitric Oxide Donors
Nitrosamines
Sulfhydryl Compounds
Nitric Oxide