N-methyl-D-aspartate antagonists and neuropathic pain: the search for relief

J Med Chem. 2007 May 31;50(11):2557-62. doi: 10.1021/jm060728b. Epub 2007 May 10.
No abstract available

Publication types

  • Review

MeSH terms

  • Analgesics / pharmacology*
  • Analgesics / therapeutic use
  • Analgesics, Opioid / pharmacology
  • Analgesics, Opioid / therapeutic use
  • Animals
  • Binding Sites
  • Glycine / metabolism
  • Humans
  • Ion Channel Gating / drug effects
  • Pain / drug therapy
  • Pain / metabolism
  • Pain / physiopathology*
  • Peripheral Nervous System Diseases / drug therapy
  • Peripheral Nervous System Diseases / metabolism
  • Peripheral Nervous System Diseases / physiopathology*
  • Protein Subunits / antagonists & inhibitors
  • Protein Subunits / metabolism
  • Protein Subunits / physiology
  • Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors*
  • Receptors, N-Methyl-D-Aspartate / metabolism
  • Receptors, N-Methyl-D-Aspartate / physiology

Substances

  • Analgesics
  • Analgesics, Opioid
  • NR2B NMDA receptor
  • Protein Subunits
  • Receptors, N-Methyl-D-Aspartate
  • Glycine