On the development of alternative antiepileptic drugs. Lack of enantioselectivity of the anticonvulsant activity, in contrast to teratogenicity, of 2-n-propyl-4-pentenoic acid and 2-n-propyl-4-pentynoic acid, analogues of the anticonvulsant drug valproic acid

MeSH terms

• Animals
• Anticonvulsants / therapeutic use*
• Anticonvulsants / toxicity
• Drug Design
• Fatty Acids, Monounsaturated / therapeutic use*
• Fatty Acids, Monounsaturated / toxicity
• Fatty Acids, Unsaturated / therapeutic use*
• Fatty Acids, Unsaturated / toxicity
• Female
• Mice
• Mice, Inbred Strains
• Pentylenetetrazole
• Pregnancy
• Regression Analysis
• Seizures / chemically induced
• Seizures / drug therapy*
• Stereoisomerism
• Teratogens / toxicity*
• Valproic Acid / analogs & derivatives*
• Valproic Acid / therapeutic use*
• Valproic Acid / toxicity