Bacterial invasion: entry through the exocyst door

Virginie Braun; John H Brumell

doi:10.1016/j.cub.2010.06.047

Bacterial invasion: entry through the exocyst door

Curr Biol. 2010 Aug 24;20(16):R677-9. doi: 10.1016/j.cub.2010.06.047.

Authors

Virginie Braun¹, John H Brumell

Affiliation

¹ Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada, M5G1X8.

PMID: 20728054
DOI: 10.1016/j.cub.2010.06.047

Abstract

Salmonella entry into host cells involves rearrangements of actin and mobilization of membranes. Here we discuss new findings showing that Salmonella recruits the exocyst complex, which plays a role in vesicle secretion, to the site of invasion to promote its entry.

Publication types

Comment

MeSH terms

Bacterial Proteins / metabolism*
Cell Membrane / metabolism*
Exocytosis / physiology*
Saccharomyces cerevisiae Proteins / metabolism
Saccharomyces cerevisiae Proteins / physiology
Salmonella typhimurium / metabolism
Salmonella typhimurium / physiology*
Secretory Pathway / physiology
Vesicular Transport Proteins / metabolism
Vesicular Transport Proteins / physiology
ral GTP-Binding Proteins / metabolism

Substances

Bacterial Proteins
EXO70 protein, S cerevisiae
Saccharomyces cerevisiae Proteins
Vesicular Transport Proteins
ral GTP-Binding Proteins