Abstract
The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral DNAs each have four long open reading frames, the first two corresponding to the gag and pol genes. The fourth open reading frame encodes two functional polypeptides, a large precursor of the major envelope glycoprotein and a smaller protein derived from the 3'-terminus long open reading frame analogous to the long open reading frame (lor) product of HTLV-I and -II.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Acquired Immunodeficiency Syndrome* / etiology
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Amino Acid Sequence
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Base Sequence
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Capsid / genetics
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DNA, Viral*
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Deltaretrovirus / genetics*
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Genes, Viral
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Humans
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Peptide Hydrolases / genetics
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Protein Precursors / genetics
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RNA-Directed DNA Polymerase / genetics
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Retroviridae Infections
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Viral Envelope Proteins / genetics
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Viral Proteins / genetics
Substances
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DNA, Viral
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Protein Precursors
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Viral Envelope Proteins
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Viral Proteins
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RNA-Directed DNA Polymerase
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Peptide Hydrolases
Associated data
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GENBANK/K02008
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GENBANK/K02009
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GENBANK/K02010
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GENBANK/K02011
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GENBANK/K02012
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GENBANK/K03455
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GENBANK/M15653
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GENBANK/M15654