Biological effects of the superoxide radical

Arch Biochem Biophys. 1986 May 15;247(1):1-11. doi: 10.1016/0003-9861(86)90526-6.

Abstract

Can the superoxide radical exert deleterious effects independent of participating with H2O2 in the production of the hydroxyl radical? Examination of the superoxide-related literature reveals data suggesting an affirmative answer to this question.

Publication types

  • Review

MeSH terms

  • Animals
  • Catalase / metabolism
  • Catalysis
  • Chemotactic Factors / biosynthesis
  • Erythrocytes / metabolism
  • Ferritins / metabolism
  • Glutathione Peroxidase / metabolism
  • Hemoglobins / metabolism
  • Inflammation / metabolism
  • Isoenzymes / metabolism
  • L-Lactate Dehydrogenase / metabolism
  • Lipid Peroxides / physiology
  • Lung / drug effects
  • Macrophages / drug effects
  • Molecular Weight
  • Neutrophils / physiology
  • Oxidation-Reduction
  • Oxygen / toxicity
  • Paraquat / toxicity
  • Perfusion
  • Peroxidase
  • Peroxidases / metabolism
  • Plants
  • Saccharomyces cerevisiae / metabolism
  • Shock, Hemorrhagic / metabolism
  • Stem Cells / drug effects
  • Superoxide Dismutase / metabolism
  • Superoxides / physiology*
  • Superoxides / toxicity
  • Transketolase / metabolism

Substances

  • Chemotactic Factors
  • Hemoglobins
  • Isoenzymes
  • Lipid Peroxides
  • Superoxides
  • Ferritins
  • L-Lactate Dehydrogenase
  • Peroxidases
  • pseudocatalase
  • Catalase
  • Peroxidase
  • Glutathione Peroxidase
  • Superoxide Dismutase
  • Transketolase
  • Paraquat
  • Oxygen