Towards a selective chemotherapy of virus infections. Development of bromovinyldeoxyuridine as a highly potent and selective antiherpetic drug

Verh K Acad Geneeskd Belg. 1986;48(4):261-90.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antiviral Agents / therapeutic use*
  • Bromodeoxyuridine / analogs & derivatives*
  • Bromodeoxyuridine / metabolism
  • Bromodeoxyuridine / pharmacology
  • Bromodeoxyuridine / therapeutic use
  • Cell Transformation, Neoplastic / drug effects
  • Chemical Phenomena
  • Chemistry
  • DNA-Directed DNA Polymerase / metabolism
  • Herpesviridae Infections / drug therapy*
  • Humans
  • Mice
  • Structure-Activity Relationship
  • Thymidine Kinase / metabolism
  • Viral Proteins / metabolism

Substances

  • Antiviral Agents
  • Viral Proteins
  • brivudine
  • Thymidine Kinase
  • DNA-Directed DNA Polymerase
  • Bromodeoxyuridine