Abstract
Hypopigmentation of hair and freckles occurred in a patient receiving chloroquine sulfate therapy. This patient had a severe congenital renal failure that presumably increased plasma and tissue levels of the drug substantially, accounting for the hypopigmentation.
MeSH terms
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Adolescent
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Chloroquine / adverse effects*
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Chloroquine / metabolism
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Female
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Hair / pathology
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Hair Color*
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Humans
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Kidney Failure, Chronic / complications
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Kidney Failure, Chronic / congenital
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Kidney Failure, Chronic / metabolism
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Melanosis / pathology*
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Pigmentation Disorders / chemically induced*