Measurement of hydrophobicity, surface activity, local anaesthesia, and myocardial conduction velocity as quantitative parameters of the non-specific membrane affinity of nine -adrenergic blocking agents

Naunyn Schmiedebergs Arch Pharmacol. 1973;277(2):211-26. doi: 10.1007/BF00501161.
No abstract available

MeSH terms

  • 1-Propanol / pharmacology
  • Absorption
  • Acetanilides / pharmacology
  • Adrenergic beta-Antagonists / pharmacology*
  • Alprenolol / pharmacology
  • Amino Alcohols / pharmacology
  • Anesthetics, Local / pharmacology
  • Animals
  • Anura
  • Butylamines / pharmacology
  • Cresols / pharmacology
  • Ethanolamines / pharmacology
  • Heart Conduction System / drug effects
  • In Vitro Techniques
  • Membranes / drug effects*
  • Nitrobenzenes / pharmacology
  • Oxprenolol / pharmacology
  • Phenethylamines / pharmacology
  • Phenols / pharmacology
  • Pindolol / pharmacology
  • Propranolol / pharmacology
  • Propylamines / pharmacology
  • Sotalol / pharmacology
  • Structure-Activity Relationship
  • Surface Tension
  • Surface-Active Agents / pharmacology
  • Water

Substances

  • Acetanilides
  • Adrenergic beta-Antagonists
  • Amino Alcohols
  • Anesthetics, Local
  • Butylamines
  • Cresols
  • Ethanolamines
  • Nitrobenzenes
  • Phenethylamines
  • Phenols
  • Propylamines
  • Surface-Active Agents
  • Water
  • Oxprenolol
  • Alprenolol
  • 1-Propanol
  • Propranolol
  • Sotalol
  • Pindolol