Growth hormone modulation of liver drug metabolic enzyme activity in the rat. I. Effect of the hormone on the content and rate of reduction of microsomal cytochrome P-450

Biochem Pharmacol. 1973 Jul 15;22(14):1717-28. doi: 10.1016/0006-2952(73)90385-7.
No abstract available

MeSH terms

  • Aniline Compounds / metabolism
  • Animals
  • Cytochrome P-450 Enzyme System / metabolism*
  • Cytochrome Reductases / antagonists & inhibitors
  • Cytochrome Reductases / metabolism
  • Drug Stability
  • Growth Hormone / pharmacology*
  • Hexobarbital / metabolism
  • In Vitro Techniques
  • Liver / enzymology*
  • Male
  • Microsomes, Liver / enzymology*
  • Microsomes, Liver / metabolism
  • NADP / metabolism
  • Oxidation-Reduction
  • Rats

Substances

  • Aniline Compounds
  • NADP
  • Growth Hormone
  • Cytochrome P-450 Enzyme System
  • Hexobarbital
  • Cytochrome Reductases