A model system for the study of heteroexchange diffusion: methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells

Biochim Biophys Acta. 1971 Jun 1;233(3):624-34. doi: 10.1016/0005-2736(71)90162-3.
No abstract available

MeSH terms

  • Animals
  • Binding Sites
  • Biological Transport / drug effects
  • Carbon Isotopes
  • Carcinoma, Ehrlich Tumor / metabolism*
  • Cell Line
  • Cell Membrane / metabolism
  • Cells, Cultured
  • Chromatography, DEAE-Cellulose
  • Diffusion
  • Folic Acid / isolation & purification
  • Folic Acid / metabolism*
  • Folic Acid / pharmacology
  • Folic Acid Antagonists
  • Formates / pharmacology
  • Kinetics
  • Leukemia L1210 / metabolism*
  • Methotrexate / metabolism*
  • Methotrexate / pharmacology
  • Methylation
  • Mice
  • Models, Biological
  • Tritium

Substances

  • Carbon Isotopes
  • Folic Acid Antagonists
  • Formates
  • Tritium
  • Folic Acid
  • Methotrexate