Abstract
Caveolae are essential endocytic organelles that use glycosyl-phosphatidyl-inositol (GPI)-anchored membrane proteins to concentrate low molecular weight substances before delivery to the cell. Caveolae and GPI-anchored proteins are uniquely adapted for this task. Recent advances suggest that this endocytic pathway also has an important role in modulating the interaction of a cell with its environment. Many vital functions that occur in this organelle remain to be discovered.
MeSH terms
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Animals
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CSK Tyrosine-Protein Kinase
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Calcium Channels / analysis
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Cell Membrane / ultrastructure*
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Glycosylphosphatidylinositols / chemistry*
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Humans
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Inositol 1,4,5-Trisphosphate
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Inositol 1,4,5-Trisphosphate Receptors
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Membrane Proteins / chemistry*
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Organelles / ultrastructure*
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Protein-Tyrosine Kinases / chemistry
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Proto-Oncogene Proteins pp60(c-src) / chemistry
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Receptors, Cytoplasmic and Nuclear / analysis
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src-Family Kinases
Substances
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Calcium Channels
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Glycosylphosphatidylinositols
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ITPR1 protein, human
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Inositol 1,4,5-Trisphosphate Receptors
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Membrane Proteins
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Receptors, Cytoplasmic and Nuclear
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Inositol 1,4,5-Trisphosphate
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Protein-Tyrosine Kinases
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CSK Tyrosine-Protein Kinase
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Proto-Oncogene Proteins pp60(c-src)
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src-Family Kinases
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CSK protein, human