Advances in glyoxalase research. Glyoxalase expression in malignancy, anti-proliferative effects of methylglyoxal, glyoxalase I inhibitor diesters and S-D-lactoylglutathione, and methylglyoxal-modified protein binding and endocytosis by the advanced glycation endproduct receptor

Crit Rev Oncol Hematol. 1995 Aug;20(1-2):99-128. doi: 10.1016/1040-8428(94)00149-n.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Endocytosis / drug effects
  • Endocytosis / physiology
  • Esters / pharmacology
  • Glutathione / analogs & derivatives*
  • Glutathione / pharmacology
  • Glycation End Products, Advanced / metabolism*
  • Humans
  • Lactoylglutathione Lyase / antagonists & inhibitors
  • Lactoylglutathione Lyase / metabolism
  • Lactoylglutathione Lyase / physiology*
  • Neoplasms / drug therapy
  • Neoplasms / enzymology*
  • Neoplasms / metabolism
  • Protein Binding / drug effects
  • Pyruvaldehyde / pharmacology*
  • Receptors, Cell Surface / metabolism
  • Thiolester Hydrolases / metabolism
  • Thiolester Hydrolases / physiology*

Substances

  • Antineoplastic Agents
  • Esters
  • Glycation End Products, Advanced
  • Receptors, Cell Surface
  • Pyruvaldehyde
  • Thiolester Hydrolases
  • hydroxyacylglutathione hydrolase
  • Lactoylglutathione Lyase
  • Glutathione
  • S-lactoylglutathione