Antagonism of the synaptic depressant actions of L-AP4 in the lateral perforant path by MAP4

T J Bushell; D E Jane; H W Tse; J C Watkins; C H Davies; J Garthwaite; G L Collingridge

doi:10.1016/0028-3908(95)00012-u

Antagonism of the synaptic depressant actions of L-AP4 in the lateral perforant path by MAP4

Neuropharmacology. 1995 Feb;34(2):239-41. doi: 10.1016/0028-3908(95)00012-u.

Authors

T J Bushell¹, D E Jane, H W Tse, J C Watkins, C H Davies, J Garthwaite, G L Collingridge

Affiliation

¹ Department of Anatomy, University of Bristol, School of Medical Sciences, U.K.

PMID: 7617150
DOI: 10.1016/0028-3908(95)00012-u

Abstract

A new mGluR antagonist, MAP4 (the alpha-methyl derivative of L-AP4), was found to antagonize the synaptic depressant actions of L-AP4 at the lateral perforant path synapse, in rat hippocampal slices.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Butyrates / pharmacology*
Butyric Acid
Hippocampus / drug effects
Membrane Potentials / drug effects*
Microtubule-Associated Proteins / pharmacology*
Rats
Rats, Wistar
Synaptic Transmission / drug effects
Time Factors

Substances

Butyrates
Microtubule-Associated Proteins
Butyric Acid