Abstract
Recent findings have revealed much about the structure of involucrin. These findings make it possible to propose specific models regarding the role of involucrin and the mechanism of its crosslinking as an envelope precursor. These models provide clearly testable hypotheses that are expected to provide additional insights into the mechanism of cornified envelope assembly.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Amino Acid Sequence
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Animals
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Humans
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Models, Chemical
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Molecular Sequence Data
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Protein Precursors / chemistry*
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Protein Precursors / genetics
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Protein Precursors / physiology*
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Skin / cytology
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Skin Physiological Phenomena*
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Transglutaminases / physiology
Substances
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Protein Precursors
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involucrin
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Transglutaminases