The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones

J Med Chem. 1996 Feb 2;39(3):665-8. doi: 10.1021/jm950395a.

Authors

T M Willson¹, J E Cobb, D J Cowan, R W Wiethe, I D Correa, S R Prakash, K D Beck, L B Moore, S A Kliewer, J M Lehmann

Affiliation

¹ Glaxo Wellcome Research and Development, Research Triangle Park, North Carolina 27709, USA.

PMID: 8576907
DOI: 10.1021/jm950395a

No abstract available

MeSH terms

Animals
Cell Line
Hypoglycemic Agents / chemistry*
Hypoglycemic Agents / pharmacology*
Mice
Receptors, Cytoplasmic and Nuclear / agonists*
Structure-Activity Relationship
Thiazoles / chemistry*
Thiazoles / pharmacology*
Transcription Factors / agonists*

Substances

Hypoglycemic Agents
Receptors, Cytoplasmic and Nuclear
Thiazoles
Transcription Factors