Further identification of PGE1 metabolites formed in the cat lung

Can J Physiol Pharmacol. 1977 Apr;55(2):311-3. doi: 10.1139/y77-045.

Abstract

Tritium-labeled compounds appearing in the venous effluent of isolated blood perfused cat lungs after infusion of [3H]prostaglandin E1 (PGE1) appear to be unchanged [3H]PGE1 and 13,14-dihydro-15-keto-PGE1. No 15-keto-PGE1 could be detected in the venous effluent.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cats
  • Chromatography, Thin Layer
  • In Vitro Techniques
  • Lung / metabolism*
  • Prostaglandins E / blood
  • Prostaglandins E / metabolism*
  • Time Factors
  • Tritium

Substances

  • Prostaglandins E
  • Tritium