Mechanisms of beta-adrenergic receptor desensitization and resensitization

Adv Pharmacol. 1998:42:416-20. doi: 10.1016/s1054-3589(08)60777-2.

Authors

R J Lefkowitz¹, J Pitcher, K Krueger, Y Daaka

Affiliation

¹ Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

PMID: 9327928
DOI: 10.1016/s1054-3589(08)60777-2

No abstract available

MeSH terms

Animals
Binding Sites
Brain / enzymology
Cattle
GTP-Binding Proteins / chemistry
GTP-Binding Proteins / metabolism
Liposomes
Macromolecular Substances
Models, Biological
Models, Structural
Phosphatidylcholines
Phosphatidylinositol 4,5-Diphosphate / metabolism
Phosphoprotein Phosphatases / metabolism
Phosphorylation
Protein Conformation
Protein Kinases / metabolism
Receptors, Adrenergic, beta-2 / chemistry
Receptors, Adrenergic, beta-2 / physiology*

Substances

Liposomes
Macromolecular Substances
Phosphatidylcholines
Phosphatidylinositol 4,5-Diphosphate
Receptors, Adrenergic, beta-2
Protein Kinases
Phosphoprotein Phosphatases
GTP-Binding Proteins