Crystal structure of estrogen sulphotransferase

Nat Struct Biol. 1997 Nov;4(11):904-8. doi: 10.1038/nsb1197-904.

Abstract

The structure of estrogen sulphotransferase has been solved in the presence of inactive cofactor PAP and substrate 17 beta-estradiol. This structure reveals structural similarities between cytosolic sulphotransferases and nucleotide kinases.

Publication types

  • Letter
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Binding Sites
  • Crystallography, X-Ray
  • Mice
  • Models, Molecular
  • Molecular Sequence Data
  • Protein Conformation*
  • Protein Folding
  • Protein Structure, Secondary*
  • Sulfotransferases / chemistry*

Substances

  • Sulfotransferases
  • estrone sulfotransferase