The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26

M R Koehler; B Wissinger; V Gorboulev; H Koepsell; M Schmid

doi:10.1159/000134720

The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26

Cytogenet Cell Genet. 1997;79(3-4):198-200. doi: 10.1159/000134720.

Authors

M R Koehler¹, B Wissinger, V Gorboulev, H Koepsell, M Schmid

Affiliation

¹ Department of Human Genetics, University of Würzburg, Biozentrum, Germany.

PMID: 9605850
DOI: 10.1159/000134720

Abstract

Polyspecific transporters for organic cations (OCT) belong to a new protein family which also include organic anion transporters. The first human transporters from this family (OCT1, OCT2) have been recently cloned. They translocate small cations like tetraethylammonium, choline and monoamine neurotransmitters and are involved in hepatic and renal cation excretion, respectively. We have localized the OCT1 and OCT2 genes (SLC22A1, SLC22A2) on chromosome 6q26.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Carrier Proteins / genetics*
Chaperonin Containing TCP-1
Chaperonins
Chromosome Mapping
Chromosomes, Human, Pair 6*
Heat-Shock Proteins / genetics*
Humans
Molecular Chaperones / genetics*
Organic Cation Transport Proteins*
Organic Cation Transporter 2
Polymerase Chain Reaction

Substances

Carrier Proteins
Heat-Shock Proteins
Molecular Chaperones
Organic Cation Transport Proteins
Organic Cation Transporter 2
SLC22A2 protein, human
Chaperonin Containing TCP-1
Chaperonins