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Page 1
Debenzylative Cycloetherification as a Synthetic Tool in the Diastereoselective Synthesis of 3,6-Disubstituted Hexahydro-2H-furo[3,2-b]pyrroles, PDE1 Enzyme Inhibitors with an Antiproliferative Effect on Melanoma Cells.
Castán A, Badorrey R, Díez JA, Christoffersen CT, Rasmussen LK, Kehler J, Köhler R, Gálvez JA, Díaz-de-Villegas MD. Castán A, et al. Among authors: badorrey r. J Org Chem. 2020 May 1;85(9):5941-5951. doi: 10.1021/acs.joc.0c00276. Epub 2020 Apr 16. J Org Chem. 2020. PMID: 32248689
Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.
Oliván-Viguera A, Valero MS, Pinilla E, Amor S, García-Villalón ÁL, Coleman N, Laría C, Calvín-Tienza V, García-Otín ÁL, Fernández-Fernández JM, Murillo MD, Gálvez JA, Díaz-de-Villegas MD, Badorrey R, Simonsen U, Rivera L, Wulff H, Köhler R. Oliván-Viguera A, et al. Among authors: badorrey r. Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):184-92. doi: 10.1111/bcpt.12560. Epub 2016 Feb 29. Basic Clin Pharmacol Toxicol. 2016. PMID: 26821335 Free PMC article.
A novel pan-negative-gating modulator of KCa2/3 channels, fluoro-di-benzoate, RA-2, inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo.
Oliván-Viguera A, Valero MS, Coleman N, Brown BM, Laría C, Murillo MD, Gálvez JA, Díaz-de-Villegas MD, Wulff H, Badorrey R, Köhler R. Oliván-Viguera A, et al. Among authors: badorrey r. Mol Pharmacol. 2015 Feb;87(2):338-48. doi: 10.1124/mol.114.095745. Epub 2014 Dec 2. Mol Pharmacol. 2015. PMID: 25468883 Free PMC article.
19 results