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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 1
1998 1
1999 3
2000 1
2001 5
2002 4
2003 2
2004 2
2005 1
2006 4
2007 1
2008 2
2009 2
2010 1
2012 3
2013 3
2014 2
2015 5
2016 5
2017 3
2018 5
2019 1
2020 1
2021 1
2023 2
2024 1

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54 results

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Page 1
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Brown AJH, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L, Dias JM, Errey JC, Hurrell E, Liptrot J, Mattedi G, Molloy C, Nathan PJ, Okrasa K, Osborne G, Patel JC, Pickworth M, Robertson N, Shahabi S, Bundgaard C, Phillips K, Broad LM, Goonawardena AV, Morairty SR, Browning M, Perini F, Dawson GR, Deakin JFW, Smith RT, Sexton PM, Warneck J, Vinson M, Tasker T, Tehan BG, Teobald B, Christopoulos A, Langmead CJ, Jazayeri A, Cooke RM, Rucktooa P, Congreve MS, Weir M, Tobin AB. Brown AJH, et al. Among authors: broad lm. Cell. 2021 Nov 24;184(24):5886-5901.e22. doi: 10.1016/j.cell.2021.11.001. Cell. 2021. PMID: 34822784 Free article. Clinical Trial.
TRPV3 in Drug Development.
Broad LM, Mogg AJ, Eberle E, Tolley M, Li DL, Knopp KL. Broad LM, et al. Pharmaceuticals (Basel). 2016 Sep 9;9(3):55. doi: 10.3390/ph9030055. Pharmaceuticals (Basel). 2016. PMID: 27618069 Free PMC article. Review.
TRP channels as emerging targets for pain therapeutics.
Broad LM, Mogg AJ, Beattie RE, Ogden AM, Blanco MJ, Bleakman D. Broad LM, et al. Expert Opin Ther Targets. 2009 Jan;13(1):69-81. doi: 10.1517/14728220802616620. Expert Opin Ther Targets. 2009. PMID: 19063707 Review.
Mechanisms of capacitative calcium entry.
Putney JW Jr, Broad LM, Braun FJ, Lievremont JP, Bird GS. Putney JW Jr, et al. Among authors: broad lm. J Cell Sci. 2001 Jun;114(Pt 12):2223-9. doi: 10.1242/jcs.114.12.2223. J Cell Sci. 2001. PMID: 11493662 Review.
The atypical 'hippocampal' glutamate receptor coupled to phospholipase D that controls stretch-sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2.
Thompson KJ, Watson S, Zanato C, Dall'Angelo S, De Nooij JC, Pace-Bonello B, Shenton FC, Sanger HE, Heinz BA, Broad LM, Grosjean N, McQuillian JR, Dubini M, Pyner S, Greig I, Zanda M, Bleakman D, Banks RW, Bewick GS. Thompson KJ, et al. Among authors: broad lm. Exp Physiol. 2024 Jan;109(1):81-99. doi: 10.1113/EP090761. Epub 2023 Sep 1. Exp Physiol. 2024. PMID: 37656490 Review.
Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs.
Bradley SJ, Molloy C, Valuskova P, Dwomoh L, Scarpa M, Rossi M, Finlayson L, Svensson KA, Chernet E, Barth VN, Gherbi K, Sykes DA, Wilson CA, Mistry R, Sexton PM, Christopoulos A, Mogg AJ, Rosethorne EM, Sakata S, John Challiss RA, Broad LM, Tobin AB. Bradley SJ, et al. Among authors: broad lm. Nat Chem Biol. 2020 Mar;16(3):240-249. doi: 10.1038/s41589-019-0453-9. Epub 2020 Feb 20. Nat Chem Biol. 2020. PMID: 32080630 Free article.
54 results