Brumshtein B[au] - Search Results

Year	Number of Results
2002	1
2004	1
2005	3
2006	2
2007	2
2008	2
2009	2
2010	1
2011	1
2014	1
2015	1
2018	1
2023	1
2024	1

1

Acid beta-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy.

Kacher Y, Brumshtein B, Boldin-Adamsky S, Toker L, Shainskaya A, Silman I, Sussman JL, Futerman AH. Kacher Y, et al. Among authors: brumshtein b. Biol Chem. 2008 Nov;389(11):1361-9. doi: 10.1515/BC.2008.163. Biol Chem. 2008. PMID: 18783340 Review.

2

Design and Synthesis of Novel HIV-1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties.

Prener L, Baszczyňski O, Kaiser MM, Dračínský M, Stepan G, Lee YJ, Brumshtein B, Yu H, Jansa P, Lansdon EB, Janeba Z. Prener L, et al. Among authors: brumshtein b. J Med Chem. 2023 Feb 9;66(3):1761-1777. doi: 10.1021/acs.jmedchem.2c01574. Epub 2023 Jan 18. J Med Chem. 2023. PMID: 36652602 Free PMC article.

3

Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.

Mulato A, Lansdon E, Aoyama R, Voigt J, Lee M, Liclican A, Lee G, Singer E, Stafford B, Gong R, Murray B, Chan J, Lee J, Xu Y, Ahmadyar S, Gonzalez A, Cho A, Stepan GJ, Schmitz U, Schultz B, Marchand B, Brumshtein B, Wang R, Yu H, Cihlar T, Xu L, Yant SR. Mulato A, et al. Among authors: brumshtein b. Antimicrob Agents Chemother. 2024 Apr 3;68(4):e0137323. doi: 10.1128/aac.01373-23. Epub 2024 Feb 21. Antimicrob Agents Chemother. 2024. PMID: 38380945 Free PMC article.

4

Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.

Brumshtein B, Esswein SR, Sawaya MR, Rosenberg G, Ly AT, Landau M, Eisenberg DS. Brumshtein B, et al. J Biol Chem. 2018 Dec 21;293(51):19659-19671. doi: 10.1074/jbc.RA118.004142. Epub 2018 Oct 24. J Biol Chem. 2018. PMID: 30355736 Free PMC article.

5

Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain.

Brumshtein B, Esswein SR, Salwinski L, Phillips ML, Ly AT, Cascio D, Sawaya MR, Eisenberg DS. Brumshtein B, et al. Elife. 2015 Nov 18;4:e10935. doi: 10.7554/eLife.10935. Elife. 2015. PMID: 26576950 Free PMC article.

6

Formation of amyloid fibers by monomeric light chain variable domains.

Brumshtein B, Esswein SR, Landau M, Ryan CM, Whitelegge JP, Phillips ML, Cascio D, Sawaya MR, Eisenberg DS. Brumshtein B, et al. J Biol Chem. 2014 Oct 3;289(40):27513-25. doi: 10.1074/jbc.M114.585638. Epub 2014 Aug 19. J Biol Chem. 2014. PMID: 25138218 Free PMC article.

7

Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.

Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RB, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS. Harel M, et al. Among authors: brumshtein b. Nat Struct Mol Biol. 2004 May;11(5):412-9. doi: 10.1038/nsmb767. Epub 2004 Apr 18. Nat Struct Mol Biol. 2004. PMID: 15098021

8

Characterization of gene-activated human acid-beta-glucosidase: crystal structure, glycan composition, and internalization into macrophages.

Brumshtein B, Salinas P, Peterson B, Chan V, Silman I, Sussman JL, Savickas PJ, Robinson GS, Futerman AH. Brumshtein B, et al. Glycobiology. 2010 Jan;20(1):24-32. doi: 10.1093/glycob/cwp138. Epub 2009 Sep 9. Glycobiology. 2010. PMID: 19741058 Free PMC article.

9

3-D structure of serum paraoxonase 1 sheds light on its activity, stability, solubility and crystallizability.

Harel M, Brumshtein B, Meged R, Dvir H, Ravelli RB, McCarthy A, Toker L, Silman I, Sussman JL. Harel M, et al. Among authors: brumshtein b. Arh Hig Rada Toksikol. 2007 Sep;58(3):347-53. doi: 10.2478/v10004-007-0028-0. Arh Hig Rada Toksikol. 2007. PMID: 17913690 Free article.

10

Structural comparison of differently glycosylated forms of acid-beta-glucosidase, the defective enzyme in Gaucher disease.

Brumshtein B, Wormald MR, Silman I, Futerman AH, Sussman JL. Brumshtein B, et al. Acta Crystallogr D Biol Crystallogr. 2006 Dec;62(Pt 12):1458-65. doi: 10.1107/S0907444906038303. Epub 2006 Nov 23. Acta Crystallogr D Biol Crystallogr. 2006. PMID: 17139081

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