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Page 1
Antimicrobial combinations against Helicobacter pylori including benzoxadiazol-based flavodoxin inhibitors: in vitro characterization.
Beyria L, Gourbeyre O, Salillas S, Mahía A, Díaz de Villegas MD, Aínsa JA, Sancho J, Bousquet-Mélou A, Ferran AA. Beyria L, et al. Among authors: diaz de villegas md. Microbiol Spectr. 2024 Jan 11;12(1):e0262323. doi: 10.1128/spectrum.02623-23. Epub 2023 Dec 12. Microbiol Spectr. 2024. PMID: 38084974 Free PMC article.
Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability.
Mahía A, Peña-Díaz S, Navarro S, José Galano-Frutos J, Pallarés I, Pujols J, Díaz-de-Villegas MD, Gálvez JA, Ventura S, Sancho J. Mahía A, et al. Among authors: diaz de villegas md. Bioorg Chem. 2021 Dec;117:105472. doi: 10.1016/j.bioorg.2021.105472. Epub 2021 Nov 6. Bioorg Chem. 2021. PMID: 34775206 Free article.
Debenzylative Cycloetherification as a Synthetic Tool in the Diastereoselective Synthesis of 3,6-Disubstituted Hexahydro-2H-furo[3,2-b]pyrroles, PDE1 Enzyme Inhibitors with an Antiproliferative Effect on Melanoma Cells.
Castán A, Badorrey R, Díez JA, Christoffersen CT, Rasmussen LK, Kehler J, Köhler R, Gálvez JA, Díaz-de-Villegas MD. Castán A, et al. Among authors: diaz de villegas md. J Org Chem. 2020 May 1;85(9):5941-5951. doi: 10.1021/acs.joc.0c00276. Epub 2020 Apr 16. J Org Chem. 2020. PMID: 32248689
Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7-Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains and in Helicobacter pylori-Infected Mice.
Salillas S, Alías M, Michel V, Mahía A, Lucía A, Rodrigues L, Bueno J, Galano-Frutos JJ, De Reuse H, Velázquez-Campoy A, Carrodeguas JA, Sostres C, Castillo J, Aínsa JA, Díaz-de-Villegas MD, Lanas Á, Touati E, Sancho J. Salillas S, et al. Among authors: diaz de villegas md. J Med Chem. 2019 Jul 11;62(13):6102-6115. doi: 10.1021/acs.jmedchem.9b00355. Epub 2019 Jun 21. J Med Chem. 2019. PMID: 31244111 Free article.
Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies.
Salillas S, Galano-Frutos JJ, Mahía A, Maity R, Conde-Giménez M, Anoz-Carbonell E, Berlamont H, Velazquez-Campoy A, Touati E, Mamat U, Schaible UE, Gálvez JA, Díaz-de-Villegas MD, Haesebrouck F, Aínsa JA, Sancho J. Salillas S, et al. Among authors: diaz de villegas md. Int J Mol Sci. 2021 Sep 20;22(18):10137. doi: 10.3390/ijms221810137. Int J Mol Sci. 2021. PMID: 34576300 Free PMC article.
Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position.
Gálvez JA, Clavería-Gimeno R, Galano-Frutos JJ, Sancho J, Velázquez-Campoy A, Abian O, Díaz-de-Villegas MD. Gálvez JA, et al. Among authors: diaz de villegas md. Eur J Med Chem. 2019 Jun 1;171:401-419. doi: 10.1016/j.ejmech.2019.03.019. Epub 2019 Mar 12. Eur J Med Chem. 2019. PMID: 30928711
Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.
Oliván-Viguera A, Valero MS, Pinilla E, Amor S, García-Villalón ÁL, Coleman N, Laría C, Calvín-Tienza V, García-Otín ÁL, Fernández-Fernández JM, Murillo MD, Gálvez JA, Díaz-de-Villegas MD, Badorrey R, Simonsen U, Rivera L, Wulff H, Köhler R. Oliván-Viguera A, et al. Among authors: diaz de villegas md. Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):184-92. doi: 10.1111/bcpt.12560. Epub 2016 Feb 29. Basic Clin Pharmacol Toxicol. 2016. PMID: 26821335 Free PMC article.
30 results