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2000 | 1 |
2002 | 3 |
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Page 1
Structure-activity relationship studies of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: an inhibitor of AP-1 and NF-kappaB mediated gene expression.
Bioorg Med Chem Lett. 2002 Sep 16;12(18):2573-7. doi: 10.1016/s0960-894x(02)00517-6.
Bioorg Med Chem Lett. 2002.
PMID: 12182863
Differential response of estrogen receptors alpha and beta to SP500263, a novel potent selective estrogen receptor modulator.
Brady H, Doubleday M, Gayo-Fung LM, Hickman M, Khammungkhune S, Kois A, Lipps S, Pierce S, Richard N, Shevlin G, Sutherland MK, Anderson DW, Bhagwat SS, Stein B.
Brady H, et al. Among authors: gayo fung lm.
Mol Pharmacol. 2002 Mar;61(3):562-8. doi: 10.1124/mol.61.3.562.
Mol Pharmacol. 2002.
PMID: 11854436
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Inhibitors of NF-kappaB and AP-1 gene expression: SAR studies on the pyrimidine portion of 2-chloro-4-trifluoromethylpyrimidine-5-[N-(3', 5'-bis(trifluoromethyl)phenyl)carboxamide].
Palanki MS, Erdman PE, Gayo-Fung LM, Shevlin GI, Sullivan RW, Goldman ME, Ransone LJ, Bennett BL, Manning AM, Suto MJ.
Palanki MS, et al. Among authors: gayo fung lm.
J Med Chem. 2000 Oct 19;43(21):3995-4004. doi: 10.1021/jm0001626.
J Med Chem. 2000.
PMID: 11052805
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Effects of SP500263, a novel selective estrogen receptor modulator, on bone, uterus, and serum cholesterol in the ovariectomized rat.
Sutherland MK, Brady H, Gayo-Fung LM, Leisten J, Lipps SG, McKie JA, O'Leary E, Patnaik N, Anderson DW, Bhagwat SS, Stein B.
Sutherland MK, et al. Among authors: gayo fung lm.
Calcif Tissue Int. 2003 Jun;72(6):710-6. doi: 10.1007/s00223-002-1029-2.
Calcif Tissue Int. 2003.
PMID: 14563000
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Effects of SP500263, a novel, potent antiestrogen, on breast cancer cells and in xenograft models.
Brady H, Desai S, Gayo-Fung LM, Khammungkhune S, McKie JA, O'Leary E, Pascasio L, Sutherland MK, Anderson DW, Bhagwat SS, Stein B.
Brady H, et al. Among authors: gayo fung lm.
Cancer Res. 2002 Mar 1;62(5):1439-42.
Cancer Res. 2002.
PMID: 11888917
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SP500263, a novel SERM, blocks osteoclastogenesis in a human bone cell model: role of IL-6 and GM-CSF.
Kung Sutherland MS, Lipps SG, Patnaik N, Gayo-Fung LM, Khammungkune S, Xie W, Brady HA, Barbosa MS, Anderson DW, Stein B.
Kung Sutherland MS, et al. Among authors: gayo fung lm.
Cytokine. 2003 Jul;23(1-2):1-14. doi: 10.1016/s1043-4666(03)00179-0.
Cytokine. 2003.
PMID: 12901849
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