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Development of Large-Scale Downstream Processing for Lentiviral Vectors.
Valkama AJ, Oruetxebarria I, Lipponen EM, Leinonen HM, Käyhty P, Hynynen H, Turkki V, Malinen J, Miinalainen T, Heikura T, Parker NR, Ylä-Herttuala S, Lesch HP. Valkama AJ, et al. Among authors: hynynen h. Mol Ther Methods Clin Dev. 2020 Mar 30;17:717-730. doi: 10.1016/j.omtm.2020.03.025. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32346549 Free PMC article.
Mitochondrial NDUFA4L2 is a novel regulator of skeletal muscle mass and force.
Liu Z, Chaillou T, Santos Alves E, Mader T, Jude B, Ferreira DMS, Hynynen H, Cheng AJ, Jonsson WO, Pironti G, Andersson DC, Kenne E, Ruas JL, Tavi P, Lanner JT. Liu Z, et al. Among authors: hynynen h. FASEB J. 2021 Dec;35(12):e22010. doi: 10.1096/fj.202100066R. FASEB J. 2021. PMID: 34724256
Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells.
Leinonen HM, Lipponen EM, Valkama AJ, Hynynen H, Oruetxebarria I, Turkki V, Olsson V, Kurkipuro J, Samaranayake H, Määttä AM, Parker NR, Ylä-Herttuala S, Lesch HP. Leinonen HM, et al. Among authors: hynynen h. Mol Ther Methods Clin Dev. 2019 Aug 29;15:63-71. doi: 10.1016/j.omtm.2019.08.006. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31649956 Free PMC article.