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1989 1
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Drug features that contribute to the activity of quinolones against mammalian topoisomerase II and cultured cells: correlation between enhancement of enzyme-mediated DNA cleavage in vitro and cytotoxic potential.
Elsea SH, McGuirk PR, Gootz TD, Moynihan M, Osheroff N. Elsea SH, et al. Among authors: mcguirk pr. Antimicrob Agents Chemother. 1993 Oct;37(10):2179-86. doi: 10.1128/AAC.37.10.2179. Antimicrob Agents Chemother. 1993. PMID: 8257142 Free PMC article.
Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury.
Farr GW, Hall CH, Farr SM, Wade R, Detzel JM, Adams AG, Buch JM, Beahm DL, Flask CA, Xu K, LaManna JC, McGuirk PR, Boron WF, Pelletier MF. Farr GW, et al. Among authors: mcguirk pr. Neuroscience. 2019 Apr 15;404:484-498. doi: 10.1016/j.neuroscience.2019.01.034. Epub 2019 Feb 7. Neuroscience. 2019. PMID: 30738082 Free PMC article.
The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest.
Wallisch JS, Janesko-Feldman K, Alexander H, Jha RM, Farr GW, McGuirk PR, Kline AE, Jackson TC, Pelletier MF, Clark RSB, Kochanek PM, Manole MD. Wallisch JS, et al. Among authors: mcguirk pr. Pediatr Res. 2019 Mar;85(4):511-517. doi: 10.1038/s41390-018-0215-5. Epub 2018 Oct 26. Pediatr Res. 2019. PMID: 30367162 Free PMC article.
18 results